Clinical Research Directory

Inclusion Criteria: 1. Older than 18 years old; 2. Sign the informed consent form; 3. Carotid occlusion at least 24h; 4. Patients with clinical localization symptoms: ipsilateral hemisphere ischemia symptoms or ipsilateral eye ischemia symptoms or cognition impairment, with or without anterior circulation blood supply area infarction; 5. DSA confirmed common carotid artery or internal carotid artery (mTICI=0) occlusion; 6. Perfusion imaging confirms the presence of hypoperfusion in the corresponding area(CBF decrease); 7. The optimal medical treatment for patients who still have ischemic symptoms; 8. Routine DWI and ADC sequence examinations are performed before surgery no new infarction; Exclusion Criteria: 1. Intracranial arteriovenous malformation or aneurysm; 2. Unstable angina, myocardial infarction (MI), or congestive heart failure in the last 6 months; 3. Uncontrolled diabetes mellitus defined as glucose \> 300 mg/dL (16.67 mmol/L); 4. Patient is expected to have the ADP antagonist therapy interruption within 3 months after the procedure; 5. Pregnant or in the perinatal period; 6. Severe concomitant disease with poor prognosis (life expectancy \< 3 years); 7. Intolerance or allergies to any of the study medications, such as aspirin or clopidogrel; 8. Allergy to iodine or radiographic contrast media; 9. Concomitant vascular conditions precluding endovascular; 10. Patients with large cerebral infarction within 2 weeks; 11. History of ipsilateral vocal cord paralysis; 12. Those with severe skin diseases who are expected to have difficulty healing the incision; 13. Poor functional status before onset (mRS score 4-5 points). 14. The area of infarction in the occluded vascular area exceeds half of the vascular supply area; 15. Already have dementia or psychiatric illness and are unable to complete neurological and cognitive assessments. 16. Any condition that in the surgeon's judgment suggests the patient an unsuitable surgical candidate.