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Subendocardial Viability Ratio in Hypertension
Sponsor: Istituto Auxologico Italiano
Summary
The aim of the research is to evaluate the Subendocardial Viability Ratio (SEVR) in hypertensive patients, using non-invasive arterial tonometry, and to establish the influencing factors and the possibility of predicting cardiovascular morbidity and mortality in arterial hypertension. The SEVR will be evaluated on all patients belonging to the Arterial Hypertension Centers undergoing non-invasive arterial tonometry. The SEVR is calculated on the morphology of the central pressure wave as the ratio between the DPTI (diastolic pressure-time index), i.e. the area between the carotid pressure curve and the ventricular pressure curve during the diastolic phase, and the SPTI ( systolic pressure-time index), i.e. the area under the carotid pressure curve during the systolic phase. The SEVR will be correlated with the anthropometric and pathology variables which will be collected in an appropriate database.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
3000
Start Date
2022-10-01
Completion Date
2026-12-31
Last Updated
2025-08-03
Healthy Volunteers
No
Conditions
Interventions
Arterial tonometry
Arterial transcutaneous tonometry
Locations (5)
Centro di Prevenzione e Cura dell'Ipertensione Arteriosa "Alessandro Filippi"
Mascalucia, Catania, Italy
Unità Operativa Semplice Dipartimentale Ipertensione Arteriosa "Anna Maria Pirrelli", Università degli Studi di Bari "Aldo Moro". Policlinico Consorziale di Bari
Bari, Italy
Istituto Auxologico Italiano IRCCS
Milan, Italy
Medicina II Cardiovascolare, AUSL-IRCCS di Reggio Emilia
Reggio Emilia, Italy
Dipartimento di Scienze Mediche, Chirurgiche e della Salute, Università degli studi di Trieste
Trieste, Italy