Clinical Research Directory

Inclusion Criteria: * Confirmation of metastatic liver cancer via histological examination or a characteristic imaging profile on dynamic computed tomography (CT) scan or magnetic resonance imaging (MRI) without indications for surgical resection * Eastern cooperative oncology group performance status (ECOGPS) of 0 or 1 * Liver function categorized as Child-Pugh class A or B * Stable non-hepatic metastases, such as skeletal, pulmonary, or lymph node metastases * Hepatic tumor burden below 70% * Expected survival duration exceeding six months * Laboratory findings meeting specific criteria, including platelet count \>50×109 /L, hemoglobin \>8.0 g/dL, ANC count ≥1.5 × 109/L, bilirubin \<51 mmol/L, alanine and aspartate aminotransferase \<3 times the upper limit of the normal range, and serum creatinine \<1.5 times the upper limit of the normal range. Exclusion Criteria: * Active infection * Presence of severe comorbidities, such as hepatic encephalopathy, refractory ascites, and esophageal variceal bleeding * Prior liver resection * Previous TACE therapy received at other healthcare facilities * Poor performance status (ECOGPS \> 1)