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RECRUITING
NCT06313957
PHASE1

A Study of LUCAR-20SP in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Sponsor: Peking University Cancer Hospital & Institute

View on ClinicalTrials.gov

Summary

This is a prospective, single-arm, open-label, exploratory clinical study of LUCAR-20SP in adult subjects with relapsed/refractory B-cell non-Hodgkin lymphoma.

Official title: A Phase I Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LUCAR-20SP, an Allogenic Chimeric Antigen Receptor(CAR)-T Cell Therapy Targeting CD20 in Subjects With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

42

Start Date

2024-03-14

Completion Date

2028-09

Last Updated

2025-03-25

Healthy Volunteers

No

Interventions

BIOLOGICAL

LUCAR-20SP cells

Prior to infusion of the LUCAR-20SP, subjects will receive a conditioning premedication regimen consisting of cyclophosphamide and fludarabine.

Locations (3)

Beijing GoBroad Boren Hospital

Beijing, Beijing Municipality, China

Peking University Cancer Hospital & Institute

Beijing, Beijing Municipality, China

Henan Cancer Hospital

Zhengzhou, China