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Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy
Sponsor: Endeavor Health
Summary
The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy. This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight. Participants will be asked to complete: * MRI in the second trimester (20-24 weeks) * MRI in the third trimester (30-34 weeks)
Key Details
Gender
FEMALE
Age Range
18 Years - 60 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2024-05-09
Completion Date
2026-12
Last Updated
2026-03-16
Healthy Volunteers
No
Conditions
Interventions
functional Magnetic Resonance Imaging (fMRI)
Participants will undergo a functional Magnetic Resonance Imaging (fMRI) using arterial spin labeling (ASL) and other Magnetic Resonance (MR) sequences
Locations (1)
Endeavor Health
Evanston, Illinois, United States