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Stage II/III Colorectal Cancer Recurrence
Sponsor: City of Hope Medical Center
Summary
This study will develop an assay to predict disease recurrence in patients with stage II/III CRC after receiving adjuvant chemotherapy, using genome-wide DNA methylation.
Official title: Predicting Recurrence-Free Survival in Stage III and High-Risk Stage II Colorectal Cancer After Curative-Intent Treatment
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
400
Start Date
2023-03-15
Completion Date
2026-06-18
Last Updated
2025-07-04
Healthy Volunteers
No
Conditions
Interventions
CENSURE
A panel of CpG sites, whose methylation level is tested in macro-dissected formalin-fixed and paraffin-embedded (FFPE) samples derived from the primary tumor.
Locations (4)
City of Hope Medical Center
Monrovia, California, United States
Second Affiliated Hospital of Dalian Medical University
Dalian, China
Barcelona University
Barcelona, Spain
La Paz University Hospital
Madrid, Spain