Clinical Research Directory

Inclusion Criteria: * Diagnosis of type 2 diabetes mellitus \> 3 months * Age≥18 years old * Receiving glucose-lowering therapy for at least 90 days * Blood glucose:7.8-22.2 mmol/L * Length of proposed hospitalisation ≥5 days Exclusion Criteria: * Type 1 diabetes mellitus, other special types of diabetes mellitus. * BG\>22.2 mmol/L, or acute complications of diabetes, such as diabetic ketoacidosis, diabetic hyperosmolar state. * History of severe or repeated hypoglycaemia * BMI≥45 kg/m2 * Pregnant and lactating women * Clinically relevant liver disease (established cirrhosis and portal hypertension); * Presence of severe renal disease (serum creatinine ≥3.0 mg/dL or estimated glomerular filtration rate \<30 ml/min/1.73 m2); * Severe cardiac insufficiency; * Patients on cortisol-based hormone therapy (equivalent to a prednisone dose \>5 mg/day); * Psychiatric abnormalities or impaired cognitive function; * Patients with severe oedema, infection, or peripheral blood circulation disorder; * Patients with severe illness or patients to be transferred to ICU for treatment; * Surgery of the heart or abdomen that may have a significant impact on the test is planned during hospitalisation.