Clinical Research Directory

Inclusion Criteria: * Must have a new diagnosis of moderate or severe OSA (i.e., AHI \> 15 events/hour). * Must be 18-70 years old. * No history of self-reported, uncontrolled, severe cardiovascular or neurological issues. * Must be able to comply with all study requirements as outlined in the consent form. * Must be able to follow the directions of the study doctor and research team. * Must be able to understand English and be willing to provide informed consent. Exclusion Criteria: * Prior use of PAP machines. * Subjects actively using bi-level PAP or require oxygen therapy. * Subjects who are medically complicated or who are medically unstable ( i.e., cancer, dementia, unstable cardiac or respiratory disease, or unstable psychiatric illness). * Potential sleep apnea complications that, in the opinion of the clinician, may affect the health and safety of the participant. * Inability or unwillingness to given written informed consent. * Neuromuscular disease, hypoglossal-nerve palsy, severe restrictive or obstructive pulmonary disease, moderate-to-severe pulmonary arterial hypertension, severe valvular heart disease, New York Heart Association class III or IV heart failure, recent myocardial infarction or severe cardiac arrhythmias (within the past 6 months), persistent uncontrolled hypertension despite medication use, active psychiatric disease, and coexisting non-respiratory sleep disorders that would confound functional sleep assessment. * Pregnancy, planning to attempt to become pregnant, or breastfeeding.