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RECRUITING
NCT06320041
PHASE4

Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery

Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

View on ClinicalTrials.gov

Summary

The goal of this clinical trial\] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new options for clinical treatment, and provides a scientific basis for clinical practice. Participants will be asked to pain score in the different time, treatments they'll be given and use optimal drug. Researchers will compare analgesic effect of oxelidine of different dose.

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

INTERVENTIONAL

Enrollment

162

Start Date

2024-08-01

Completion Date

2026-12-31

Last Updated

2025-02-17

Healthy Volunteers

No

Interventions

DRUG

Low dose oxelidine group

Analgesic dose

DRUG

High dose oxelidine group

Analgesic dose

DRUG

Hydromorphone group

Analgesic dose

Locations (1)

The Fourth Affiliated Hospital of Zhejiang University School of Medicine

Yiwu, Zhejiang, China