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Efficacy and Safety of Oliceridine for Moderate to Severe Acute Pain After Orthopedic Surgery
Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Summary
The goal of this clinical trial\] is to further explore the effectiveness and safety of oxelidine in the treatment of moderate to severe acute pain after orthopedic surgery. The main question it aims to answer is: Pain management after orthopaedic surgery provides more effective and safe drug options, provides new options for clinical treatment, and provides a scientific basis for clinical practice. Participants will be asked to pain score in the different time, treatments they'll be given and use optimal drug. Researchers will compare analgesic effect of oxelidine of different dose.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
162
Start Date
2024-08-01
Completion Date
2026-12-31
Last Updated
2025-02-17
Healthy Volunteers
No
Conditions
Interventions
Low dose oxelidine group
Analgesic dose
High dose oxelidine group
Analgesic dose
Hydromorphone group
Analgesic dose
Locations (1)
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Yiwu, Zhejiang, China