Clinical Research Directory
Browse clinical research sites, groups, and studies.
Effects of Remote Ischaemic Preconditioning in Cemented Hip Arthroplasty.
Sponsor: University of Tartu
Summary
Total joint arthroplasty is one of the best treatment options for end-stage osteoarthritis. Cemented hip arthroplasty is mainly indicated for elderly patients with poor bone quality and multiple comorbidities. Bone cement implantation syndrome is associated with cemented hip arthroplasty and it has been shown to increase cardiovascular and renal complication and brain damage postoperatively. The aim of this project is to elucidate whether remote-ischemic preconditioning (RIPC) has multi-organ protective effect in cemented hip arthroplasty patients.
Official title: Effects of Remote Ischaemic Preconditioning in Cemented Total Hip Arthroplasty: Randomized Controlled Trial
Key Details
Gender
All
Age Range
65 Years - 90 Years
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2024-03-20
Completion Date
2027-03
Last Updated
2024-04-04
Healthy Volunteers
No
Conditions
Interventions
Remote Ischemic Preconditioning
4 cycles of 5 min pressure (produces an ischemia episode in subject's upper limb) with AutoRIC device (Starfish Medical, Canada)
SHAM
4 cycles of 5min light pressure (no ischemia produced) with AutoRIC device (Starfish Medical, Canada) to imitate the RIPC procedure
Locations (1)
University of Tartu
Tartu, Tartu, Estonia