Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in People With Type 2 Diabetes Treated With Diet and Exercise
Sponsor: Novo Nordisk A/S
Summary
This study will look at how much CagriSema helps participants with type 2 diabetes lower their blood sugar and body weight. CagriSema is a new investigational medicine. Doctors may not yet prescribe CagriSema. CagriSema will be compared to a "dummy" medicine (also called "placebo") that has no effect on the body. Participants will get either CagriSema or "dummy" medicine. Which treatment participants get is decided by chance. For each participant, the study will last for about one year.
Official title: Efficacy and Safety of Co-administered Cagrilintide and Semaglutide (CagriSema) s.c. in Doses 2.4 mg/2.4 mg and 1.0 mg/1.0 mg Once Weekly Versus Placebo in Participants With Type 2 Diabetes Inadequately Controlled on Diet and Exercise
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
189
Start Date
2024-03-19
Completion Date
2025-12-22
Last Updated
2026-09-30
Healthy Volunteers
No
Conditions
Interventions
Cagrilintide
Participants will receive once-weekly cagrilintide subcutaneously.
Semaglutide
Participants will receive once-weekly semaglutide subcutaneously.
Placebo
Participants will receive placebo matched to cagrilintide and semaglutide subcutaneously.
Locations (50)
Nat Res Inst Huntington Park
Huntington Park, California, United States
Valley Clinical Trials, Inc.
Northridge, California, United States
Southern California Dermatology
Santa Ana, California, United States
Encore Medical Research LLC
Hollywood, Florida, United States
Headlands Research Orlando
Orlando, Florida, United States
Encore Medical Research of Weston
Weston, Florida, United States
Alliance for Multispec Res
Newton, Kansas, United States
Brigham & Women's Hospital
Boston, Massachusetts, United States
Arcturus HC PLC Troy Med Res
Troy, Michigan, United States
Southgate Medical Group, LLP
West Seneca, New York, United States
Summit Research Network Oregon Inc.
Portland, Oregon, United States
Holston Medical Group
Kingsport, Tennessee, United States
Amarillo Medical Specialists
Amarillo, Texas, United States
Elligo Clin Res Centre
Austin, Texas, United States
Headlands Research Brownsville
Brownsville, Texas, United States
Velocity Clinical Res-Dallas
Dallas, Texas, United States
Northeast Clinical Research of San Antonio
San Antonio, Texas, United States
Consano Clinical Research, LLC
Shavano Park, Texas, United States
Sugar Lakes Family Practice PA
Sugar Land, Texas, United States
Valley Diab. & Endo Comp Ctr
Weslaco, Texas, United States
TPMG Clinical Research
Newport News, Virginia, United States
Chinese People's Liberation Army General Hospital-Endocrinology
Beijing, Beijing Municipality, China
The Second Affiliated Hospital of Nanjing Medical University-Endocrinology
Nanjing, Jiangsu, China
The Affiliated Hospital of Jiangsu University-Endocrinology
Zhenjiang, Jiangsu, China
Jinan Central Hospital
Ji'Nan, Shandong, China
Jinan Central Hospital
Jinan, Shandong, China
Belinus Bt.
Debrecen, Hajdú-Bihar, Hungary
Borbánya Praxis E.Ü. Kft.
Nyíregyháza, Szabolcs-Szatmar Varmegye, Hungary
Szent Margit Rendelőintézet Nonprofit Kft.
Budapest, Hungary
PVN Kutató Kft.
Budapest, Hungary
Azienda Ospedaliera Papa Giovanni XXIII
Bergamo, Italy
Policlinico Mater Domini Università di Catanzaro
Catanzaro, Italy
IRCCS Ospedale San Raffaele Milano
Milan, Italy
Azienda Ospealiero Universitaria Policlinico Umberto I
Roma, Italy
Centrum Medyczne Medyk Sp. z o.o.
Rzeszów, Podkarpackie Voivodeship, Poland
Osteo-Medic s.c. A. Racewicz, J. Supronik
Bialystok, Poland
Renew Clinic Sp. z o.o.
Bialystok, Poland
Centrum Terapii Wspolczesnej J.M. Jasnorzewska S.K.A.
Lodz, Poland
NBR Polska Tomasz Klodawski
Warsaw, Poland
Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji
Warsaw, Poland
Velocity Nova Sp. z o.o.
Zamość, Poland
King Abdulaziz Hospital-Al Ahsa-National Guard
Al Ahsa, Saudi Arabia
National Guard Hospital - Jeddah
Jeddah, Saudi Arabia
King Fahad Medical City
Riyadh, Saudi Arabia
King Khaled University Hospital,King Saud Univ. Med. City
Riyadh, Saudi Arabia
King Salman Bin Abdulaziz Hospital
Riyadh, Saudi Arabia
CHC Zvezdara, Clinical department for endocrinology
Belgrade, Serbia
Clinical Hospital Center Bezanijska Kosa
Belgrade, Serbia
Clinical Hospital Centre Zemun
Belgrade, Serbia
Policlinic for diabetes
Zaječar, Serbia