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ACTIVE NOT RECRUITING
NCT06324968
NA

Ro60 Expression in Macrophages in Sjogren's Disease

Sponsor: Centre Hospitalier Universitaire de Nice

View on ClinicalTrials.gov

Summary

Context: The Ro60 protein associates with YRNAs (or RNYs) to form the RoRNP complex, which regulates RNA surveillance and maturation. It is hypothesized that its impairment by nuclear penetration of the anti-Ro60 autoantibodies, would deregulate the anti-inflammatory response in monocytes/macrophages (Mo/Mp) in patients with Sjögren's disease (SD).

Official title: Ro60 Expression in Macrophages in Patients with Primary Sjogren's Syndrome

Key Details

Gender

All

Age Range

18 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-02-09

Completion Date

2025-05-09

Last Updated

2025-03-11

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Positive serology for anti-SSA

Blood sample which detect serology for anti-SSA.

Locations (1)

CHU Nice

Nice, Alpes-Mritimes, France