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Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
Sponsor: University of Aarhus
Summary
100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1. The aim is to examine and quantify the cardiovascular and lymphatic system in women with TS. The investigators will study a possible causal mechanism between the known pathologic phenotype and alterations in these systems to understand, prevent or treat the life-threatening complications in TS.
Key Details
Gender
FEMALE
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2024-01-08
Completion Date
2027-08
Last Updated
2024-03-22
Healthy Volunteers
Yes
Interventions
No intervention other than obtaining biopsies
Skin, fat, and muscle biopsies will be obtained
Indocyanine green (ICG)
Indocyanine green will be injected to evaluate the lymphatic system.
Locations (1)
Aarhus University Hospital
Aarhus N, Denmark