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RECRUITING
NCT06326996
EARLY_PHASE1

Thiamine Intervention and Coronary Artery Bypass Grafting

Sponsor: University of California, Los Angeles

View on ClinicalTrials.gov

Summary

The purpose of this study is to gain a better understanding of the association between brain changes and cognitive deficits in coronary heart disease (CHD) patients undergoing coronary artery bypass grafting (CABG) and whether a low-cost thiamine intervention can be used to reduce post-CABG cognitive issues in CHD subjects.

Official title: Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting - A Randomized Clinical Trial.

Key Details

Gender

All

Age Range

60 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

52

Start Date

2024-10-10

Completion Date

2026-09-30

Last Updated

2025-08-01

Healthy Volunteers

No

Interventions

DRUG

Thiamine

Participants will be given an infusion of thiamine.

DRUG

Placebo

Participants will be given an infusion of the placebo treatment.

Locations (1)

UCLA

Los Angeles, California, United States