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Methimazole in Graves' Disease - Comparing the Computer-aided Treatment DigiThy Versus Usual Care
Sponsor: Medical University of Graz
Summary
The goal of this clinical trial is to compare two methods of guiding methimazole therapy in patients with Graves' disease: methimazole dose adjustments based on a new semi-automated computer-guided treatment (based on a mathematical model) or based on the treating physician's decision (i.e. usual care). The main question it aims to answer is whether semi-automated computer-guided treatment is not inferior to usual care in terms of safety, the time it takes to achieve euthyroidism and the methimazole dose required.
Official title: Guiding Methimazole Therapy in Graves' Disease - a Randomised Controlled Trial Comparing a Computer-aided Treatment (Digital Thyroid, DigiThy) Versus Usual Care
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2024-09-01
Completion Date
2026-10-01
Last Updated
2024-05-16
Healthy Volunteers
No
Conditions
Interventions
Semi-automated computer-aided treatment (Digital Thyroid, DigiThy)
Semi-automated computer-aided treatment based on a mathematical model
Usual care
Guiding methimazole therapy based on the treating physician's decision
Locations (1)
Medical University of Graz
Graz, Austria