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Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release
Sponsor: Dartmouth-Hitchcock Medical Center
Summary
The goal of this study is to learn about preventing recurrence of Dupuytren's Contracture. The main question it aims to answer are: • Does targeted radiation therapy decrease recurrence of Dupuytren's contracture after treatment with Collagenase Clostridium Histolyticum? Participants will undergo: * Release of Dupuytren's Contracture after Collagenase Clostridium Histolyticum injection * Daily radiation therapy treatment for 5 days followed by 6-8 week rest period and then another course of 5 days of radiation therapy
Official title: A Prospective Clinical Trial of Radiation Therapy for Dupuytren's Contracture Following Surgical and Non-Surgical Release
Key Details
Gender
All
Age Range
45 Years - Any
Study Type
INTERVENTIONAL
Enrollment
95
Start Date
2024-09-16
Completion Date
2032-04
Last Updated
2024-11-22
Healthy Volunteers
Yes
Conditions
Interventions
Radiation therapy
Patients with Dupuytren's Contacture will undergo Collagenase Clostridium Histolyticum injection and release followed by two 5-day courses of radiation therapy separated by 6-8 weeks. They will then be followed for 3 years for recurrence.
Locations (1)
Dartmouth Hitchcock
Lebanon, New Hampshire, United States