Clinical Research Directory
Browse clinical research sites, groups, and studies.
Transfusion in Cardiac Valve Surgery
Sponsor: Guangdong Provincial People's Hospital
Summary
This prospective, randomized controlled study is aimed to figure out suitable transfusion threshold in patients undergoing cardiac valve surgery under cardiopulmonary bypass(CPB). Patients are randomly assigned to restrictive and liberal transfusion group and receive blood transfusion during and after surgery. Compare primary and secondary outcomes of two groups.
Official title: A Multicenter Prospective, Randomized Controlled Study of Different Transfusion Thresholds in Cardiac Valve Surgery
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
1600
Start Date
2024-04-01
Completion Date
2027-12-30
Last Updated
2024-03-27
Healthy Volunteers
No
Interventions
Restrictive Transfusion Strategy
Blood transfusion at HCT less than 21% or Hb less than 6.0g/dL during CPB, at HCT less than 21% or Hb less than 7.0g/dL in ICU or general ward after surgery
Liberal Transfusion Strategy
Blood transfusion at HCT less than 24% or Hb less than 8.0g/dL during CPB, at HCT less than 30% or Hb less than 10.0g/dL in ICU or general ward after surgery
Locations (1)
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China