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ACTIVE NOT RECRUITING
NCT06333002

Machine Learning Model to Predict Outcome in Acute Hypoxemic Respiratory Failure

Sponsor: Dr. Negrin University Hospital

View on ClinicalTrials.gov

Summary

Acute hypoxemic respiratory failure (AHRF) is the most common cause of admission in the intensive care units (UCIs) worldwide. We will assess the value of machine learning (ML) techniques for early prediction of ICU death in 1,241 patients enrolled in the PANDORA (Prevalence AND Outcome of acute Respiratory fAilure) Study in Spain. The study was registered with ClinicalTrials.gov (NCT03145974). Our aim is to evaluate the minimum number of variables models using logistic regression and four supervised ML algorithms: Random Forest, Extreme Gradient Boosting, Support Vector Machine and Multilayer Perceptron.

Official title: Developing an Optimal Machine Learning Model to Predict ICU Outcome in Patients With Acute Hypoxemic Respiratory Failure

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

OBSERVATIONAL

Enrollment

1241

Start Date

2024-03-19

Completion Date

2026-05-30

Last Updated

2025-02-11

Healthy Volunteers

No

Interventions

OTHER

machine learning analysis

We will use robust machine learning approaches, such as Random Forest, Extreme Gradient Boosting, Support Vector Machine and Multilayer Perceptron.

Locations (8)

Hospital General Universitario de Ciudad Real

Ciudad Real, Spain

Hospital Virgen de La Luz

Cuenca, Spain

Hospital Universitario La Paz

Madrid, Spain

Hospital Universitario Puerta de Hierro

Madrid, Spain

Hospital Universitario Virgen de Arrixaca

Murcia, Spain

Hospital Universitario NS de Candelaria

Santa Cruz de Tenerife, Spain

Hospital Cinico de Valencia

Valencia, Spain

Hospital Universitario Rio Hortega

Valladolid, Spain