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A Prospective Study of Vasopressor on Cerebral Oxygenation During General Anesthesia
Sponsor: Dalian Municipal Central Hospital
Summary
The purpose of this study is to investigate whether norepinephrine(N), phenylephrine(P) or ephedrine(E) have different effect on cerebral oxygenation in abdominal surgery with propofol or sevoflurane.
Official title: Effects of Vasopressor on Cerebral Oxygenation During General Anesthesia in Abdominal Surgery
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2024-03-05
Completion Date
2025-12-05
Last Updated
2024-11-06
Healthy Volunteers
No
Conditions
Interventions
Ephedrine-P
after induction of anesthesia, use total intravenous anesthesia maintained with propofol
Phenylephrine-P
after induction of anesthesia, use total intravenous anesthesia maintained with propofol
Norepinephrine-P
after induction of anesthesia, use total intravenous anesthesia maintained with propofol
Ephedrine-S
after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane
Phenylephrine-S
after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane
Norepinephrine-S
after induction of anesthesia, use inhalation anesthesia maintained with sevoflurane
Locations (1)
Dalian Municipal Central Hospital
Dalian, Liaoning, China