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tVNS Responsiveness Testing With Pupil Size
Sponsor: Georgia Institute of Technology
Summary
The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults. The main question it aims to answer is whether pupil size response is greater with bilateral tVNS compared to unilateral tVNS. Participants will receive tVNS and sham at the outer ear unilaterally and bilaterally in resting condition. The pupil size of the participants will be recorded during tVNS.
Official title: Movement-Associated tVNS and Responsiveness Testing for Personalized Rehabilitation
Key Details
Gender
All
Age Range
18 Years - 89 Years
Study Type
INTERVENTIONAL
Enrollment
21
Start Date
2024-11-14
Completion Date
2025-10-27
Last Updated
2026-09-14
Healthy Volunteers
Yes
Conditions
Interventions
Unilateral Left tVNS stimulation
Electrical stimulation to the cymba concha and tragus of the outer ear on the left side.
Bilateral tVNS stimulation
Electrical stimulation to the cymba concha and tragus of the outer ear on both sides.
Unilateral Left Sham stimulation
Electrical stimulation to the earlobe of the outer ear on the left side.
Bilateral Sham stimulation
Electrical stimulation to the earlobe of the outer ear on both sides.
Unilateral Right tVNS stimulation
Electrical stimulation to the cymba concha and tragus of the outer ear on the right side.
Unilateral Right Sham stimulation
Electrical stimulation to the earlobe of the outer ear on the right side.
Locations (1)
Human Neuromuscular Physiology Lab
Atlanta, Georgia, United States