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COMPLETED
NCT06335199
NA

tVNS Responsiveness Testing With Pupil Size

Sponsor: Georgia Institute of Technology

View on ClinicalTrials.gov

Summary

The goal of this study is to learn about the acute pupil response to transcutaneous vagus nerve stimulation (tVNS) in stroke survivors and healthy adults. The main question it aims to answer is whether pupil size response is greater with bilateral tVNS compared to unilateral tVNS. Participants will receive tVNS and sham at the outer ear unilaterally and bilaterally in resting condition. The pupil size of the participants will be recorded during tVNS.

Official title: Movement-Associated tVNS and Responsiveness Testing for Personalized Rehabilitation

Key Details

Gender

All

Age Range

18 Years - 89 Years

Study Type

INTERVENTIONAL

Enrollment

21

Start Date

2024-11-14

Completion Date

2025-10-27

Last Updated

2026-09-14

Healthy Volunteers

Yes

Interventions

PROCEDURE

Unilateral Left tVNS stimulation

Electrical stimulation to the cymba concha and tragus of the outer ear on the left side.

PROCEDURE

Bilateral tVNS stimulation

Electrical stimulation to the cymba concha and tragus of the outer ear on both sides.

PROCEDURE

Unilateral Left Sham stimulation

Electrical stimulation to the earlobe of the outer ear on the left side.

PROCEDURE

Bilateral Sham stimulation

Electrical stimulation to the earlobe of the outer ear on both sides.

PROCEDURE

Unilateral Right tVNS stimulation

Electrical stimulation to the cymba concha and tragus of the outer ear on the right side.

PROCEDURE

Unilateral Right Sham stimulation

Electrical stimulation to the earlobe of the outer ear on the right side.

Locations (1)

Human Neuromuscular Physiology Lab

Atlanta, Georgia, United States