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COMPLETED
NCT06336018
PHASE1

A Research Study on Etavopivat in Participants With and Without Liver Disease

Sponsor: Novo Nordisk A/S

View on ClinicalTrials.gov

Summary

The study investigates an investigational drug called etavopivat in participants with hepatic impairments and participants with normal hepatic function (matched controls). During the study, all participants will be given a single oral dose of etavopivat. All participants will take the etavopivat orally together with water. After dosing, the study will last for 7 to 9 days.

Official title: A Multi-centre, Open-label, Parallel-group Study Investigating the Pharmacokinetics, Safety and Tolerability After a Single Dose of Oral Etavopivat in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Participants With Normal Hepatic Function

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

48

Start Date

2024-05-20

Completion Date

2025-08-01

Last Updated

2026-06-18

Healthy Volunteers

No

Conditions

Interventions

DRUG

Etavopivat

Participants will receive a single dose of etavopivat orally.

Locations (5)

Cure Clinical Research LLC

Orange, California, United States

Orlando Clinical Research Center

Orlando, Florida, United States

Orlando Clinical Research Center

Orlando, Florida, United States

Amer. Rrsch Corp-TX Liver Inst

San Antonio, Texas, United States

Pinnacle Clinical Research

San Antonio, Texas, United States