Clinical Research Directory

Inclusion Criteria: * Men and women; * 40 to 85 years of age (included); * Registered with the French Social Security; * Have a study partner. The study partner is required to complete several scales. If the subjects or their study partners are not able to drive, their transport fees will be reimbursed by the promotor. * Fluent in French, able to read and write; Exclusion Criteria: * Participants who have contraindications to perform an MRI scan; * Participants with significant sensory deficits that are not corrected by suitable devices. * Participants with dementia caused by a non-neurodegenerative disease, including patients with severe cerebrovascular risk factor load, in the judgment of the investigator; * Participants with other neurodegenerative disease such as Lewy body dementia and Parkinson's disease; * Participants with other serious neurological disorder such as brain tumor, stroke, epilepsy, hydrocephalus and any condition which contraindicates, in the investigator's judgment, entry to the study; * Participants with excessive alcohol intake or drug abuse, in the judgment of the investigator; * Participants who, in the opinion of the investigator, have a risk of non-compliance to the study procedures;