Clinical Research Directory

HPV Immunological Markers of Cervical Persistent Infection and Oncogenesis

Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia

Summary

The aim of this observational study is to build an immunological assay to quantify an immunoscore system for clinical practice, which could identify HPV lesions with a risk of persistent cervical infection, which represents the main predictive factor of neoplastic evolution. A pattern of host immunological factors and HPV-related parameters, in order to identify an algorithm of risk stratification and tailoring treatment will be identified. Finally, in patients with HPV infection, a virus specific immunity after vaccination will be quantified, in order to highlight those patients who have the most significant risk of infection persistence.

Key Details

Conditions

Locations (1)