Clinical Research Directory
Browse clinical research sites, groups, and studies.
Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals
Sponsor: Aalborg University
Summary
This project aims to investigate the relationship between different dimensions of catastrophizing (rumination, magnification, and helplessness) as well as some specific personality traits related to catastrophizing tendencies like anxiety sensitivity and fear sensitivity in the modulation of itch and pain intensities in an experimental setting.
Official title: Investigation of the Neurophysiological and Psychological Aspects of Itch
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
46
Start Date
2024-04-27
Completion Date
2026-12-31
Last Updated
2024-06-24
Healthy Volunteers
Yes
Interventions
Histamine
Histaminergic itch will be evoked by a 1% histamine solution. A droplet of histamine solution will be placed on the predetermined area on the forearm, and the SPT lancet will be pierced through the histamine with 120 g of pressure for 1-2 seconds.
Cowhage
25 spicules will be inserted in the center of the predefined skin area on the mandibular area. The spicules will be gently rubbed for 15-20 seconds in circular motion to facilitate epidermal penetration.
Locations (1)
Aalborg University
Aalborg, Denmark