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RECRUITING
NCT06340438
NA

Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals

Sponsor: Aalborg University

View on ClinicalTrials.gov

Summary

This project aims to investigate the relationship between different dimensions of catastrophizing (rumination, magnification, and helplessness) as well as some specific personality traits related to catastrophizing tendencies like anxiety sensitivity and fear sensitivity in the modulation of itch and pain intensities in an experimental setting.

Official title: Investigation of the Neurophysiological and Psychological Aspects of Itch

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

46

Start Date

2024-04-27

Completion Date

2026-12-31

Last Updated

2024-06-24

Healthy Volunteers

Yes

Interventions

OTHER

Histamine

Histaminergic itch will be evoked by a 1% histamine solution. A droplet of histamine solution will be placed on the predetermined area on the forearm, and the SPT lancet will be pierced through the histamine with 120 g of pressure for 1-2 seconds.

OTHER

Cowhage

25 spicules will be inserted in the center of the predefined skin area on the mandibular area. The spicules will be gently rubbed for 15-20 seconds in circular motion to facilitate epidermal penetration.

Locations (1)

Aalborg University

Aalborg, Denmark