Clinical Research Directory

Inclusion Criteria: * ASA I and ASA II children, aged 5 to 14 years who are patients of CDHC and USC with adequate eruption of permanent first or second molars for placement of sealants * These teeth will not have previous restorations, interproximal lesions, pathology, or occlusal lesions. * Behavior of the children should be within a Frankl 3 or 4 category, indicating a "positive" and "Definitely Positive" behavior rating, which would allow for safe and controlled execution of the proposed protocol * Patient must have contralateral molars in the same arch in which sealants can be placed. For example a child with #30 and #19 present will qualify for the study. Exclusion Criteria * Any tooth with previous sealant placement * Children who are allergic or intolerant to sealant material * Children who cannot tolerate a dental suction isolation system, such as DryShield isolation * Children who do not complete a prophy cup polish. * Children who present with banded or bracketed molars * Patients or Parents who cannot fully understand an English or Spanish Consent/ Assent form. Withdrawal Criteria * Patients can withdraw voluntarily at any time. * Any tooth which has progression of caries beyond ICCMS Category 3 will be withdrawn from the study. These teeth will be treated with appropriate restorative dental treatment according to the standard of care. * Any qualifying tooth that subsequently requires a restoration due to trauma will be withdrawn from the study. * Any patient with an adverse reaction to treatment will be withdrawn. This event will be reported to the IRB.