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RECRUITING
NCT06342414

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

Sponsor: City of Hope Medical Center

View on ClinicalTrials.gov

Summary

It is sometimes difficult to precisely understand whether a primary liver cancer is a hepatocellular carcinoma or a cholangiocarcinoma. The researchers will develop and validate a liquid biopsy, based on exosomal content analysis and powered by machine learning, to help clinicians differentiate these two cancers before surgery.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2024-03-15

Completion Date

2026-06-18

Last Updated

2026-04-03

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

ELUCIDATE

ELUCIDATE (Evaluation of Liver Cholangiocarcinoma Intrahepatic)

Locations (5)

City of Hope Medical Center

Duarte, California, United States

Graduate School of Medical Sciences, Kyushu University

Fukuoka, Japan

Graduate School of Medical Sciences, Kumamoto University

Kumamoto, Japan

Hokkaido University Graduate School of Medicine

Sapporo, Japan

Tokushima University

Tokushima, Japan