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Brain Criticality, Oculomotor Control, and Cognitive Effort
Sponsor: Rutgers, The State University of New Jersey
Summary
The project examines electroencephalography, MRI, and behavioral measures indexing flexibility (critical state dynamics) in the brain when healthy young adults do demanding cognitive tasks, and in response to transcranial magnetic stimulation.
Official title: Theta-burst Stimulation Modulates Criticality and Cognitive Control
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-08-01
Completion Date
2026-06-01
Last Updated
2024-08-07
Healthy Volunteers
Yes
Conditions
Interventions
transcranial magnetic stimulation
The study intervention involves modulation of cortical excitation to inhibition (E/I) balance in the right frontal eye field (FEF) by means of 2 trains of spaced continuous or intermittent theta burst stimulation (cTBS, iTBS, respectively) using a transcranial magnetic stimulation device. The endpoint of this stimulation will be a decrease (cTBS) or increase (iTBS) in the local E/I ratio that should last at least 60 minutes post-stimulation (Chung et al., 2016). In separate sessions, all participants will receive either active or stimulation to the FEF. The Investigators will contrast the effects of both iTBS and cTBS to sham stimulation and to each other.
Locations (1)
Center for Advanced Human Brain Imaging Research
Piscataway, New Jersey, United States