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Heart-brain-axis and Psychosocial Stress
Sponsor: University of Zurich
Summary
The main study objective is to prospectively determine the influence of sex-related risk factors and psychosocial variables on neuronal stress responses and myocardial perfusion in a population of 64 female and male individuals 50-75 years of age and free of cardiovascular disease.
Official title: Sex Differences in Heart-brain Crosstalk - Role of Psychosocial Stress
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
64
Start Date
2021-10-11
Completion Date
2024-11-20
Last Updated
2026-05-07
Healthy Volunteers
Yes
Interventions
Mental stress
Two consecutive validated mental stress tests, namely 1) the Montreal Imaging Stress Task consisting of two series of 15-minute mental calculation tests, without (Control Mode) and with (Stress Mode) negative feedback, respectively; and 2) the Trier Social Stress Test consisting of a 5-minute mock job interview (Speech Part) followed by a 5-minute mental calculation test (Mental Arithmetic Part).
Locations (1)
University Hospital Zurich
Zurich, Canton of Zurich, Switzerland