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Molecular Assessment for Gastro-Esophageal Cancer
Sponsor: KU Leuven
Summary
The goal of this minimally invasive interventional study is to learn if oncometabolic biomarkers, detected in the exhaled breath and blood can identify early-stage gastro-oesophageal cancer in patient at risk for gastro-oesophageal cancer. The main questions this study aims to answer: Are oncometabolites proficient and reproducible enough to function as diagnostic biomarkers? Can these biomarkers identify early-stage gastro-esophageal cancer? Researchers will compare participants with gastro-oesophageal cancer to healthy controls and participants with Barrett's esophagus to detect meaningful differences between the groups. Participants will provide a breath and blood sample during their routine standard of care visits.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2024-08-01
Completion Date
2029-07-01
Last Updated
2026-02-17
Healthy Volunteers
Yes
Interventions
Breath analysis
Detection of proteins and volatile organic compounds (oncometabolites) in the exhaled breath
Blood analysis
Detection of proteins and circulating tumor DNA (oncometabolites) in the peripheral blood
Locations (1)
University Hospitals Leuven
Leuven, Belgium