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Effect of Probiotics Before Cesarean Section on Postoperative Recovery in Pregnant Women
Sponsor: Third Affiliated Hospital, Sun Yat-Sen University
Summary
This study aims to evaluate the effect of probiotics 7 days before cesarean section (CS) on postoperative recovery and the change of gut microbiota in pregnant women. Samples were obtained from a total of 80 pregnant individuals, divided into control group and probiotics group. Anal exhaust time and first defecating time were set as the primary outcome of recovery of CS. 16S rRNA amplicon sequencing of the V4 region was analyzed to evaluate the composition of them.
Key Details
Gender
FEMALE
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2023-11-01
Completion Date
2025-10
Last Updated
2024-04-08
Healthy Volunteers
Yes
Conditions
Interventions
Probiotic Blend Oral Tablet
In our study, forty pregnant women were randomly assigned to the probiotic group, and the rest were assigned to the control group. After enrollment, pregnant women in the probiotic group received a combination of living Bifidobacterium longum (5 #106 CFU) by Neimengu Shuangqi Pharmaceutical Co., Ltd. Pregnant individuals in the probiotic group were administered four tablets three times a day (2 g/d) for seven days before surgery until the fourth day after surgery.
Locations (1)
Zhe Li
Guangzhou, Guangdong, China