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RECRUITING
NCT06349148
NA

The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients

Sponsor: SHUANG ZHENG JIA, PhD

View on ClinicalTrials.gov

Summary

The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy. LACC patients undergoing radical synchronous chemoradiotherapy will be randomized into the experimental group receiving enteral immunonutrition therapy and the control group receiving standard enteral nutrition support.The main purpose it aims to answer are:1)Can immunonutrition therapy improve patients' dose-limiting toxicity(DLT) and DLT-free survival? 2)Can immunonutrition therapy improve patients' nutritional status and quality of life?

Official title: The Effects of Immunonutrition Therapy on the Nutritional Status, Immune Function, and Quality of Life of Locally Advanced Cervical Cancer Patients With Malnutrition: an Open-label Randomized Controlled Study

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2024-01-01

Completion Date

2026-12

Last Updated

2025-12-05

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

enteral immunonutrition

Patients in this group receives 2 bottles of immunonutrients per day (Impact, Nestlé, approximately 700 kcal).

DIETARY_SUPPLEMENT

standard oral enteral nutrition

Patients in the control group receives isoenergetic standard oral enteral nutrition ( emulsion or Nutrison).

Locations (1)

Cancer Hospital, Chinese Academy of Medical Sciences

Beijing, China