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The Effects of Immunonutrition Therapy on Locally Advanced Cervical Cancer Patients
Sponsor: SHUANG ZHENG JIA, PhD
Summary
The goal of this open-label randomized control trial is to study the effect of immunonutrition in locally advanced cervical cancer (LACC) with standard concurrent chemoradiotherapy. LACC patients undergoing radical synchronous chemoradiotherapy will be randomized into the experimental group receiving enteral immunonutrition therapy and the control group receiving standard enteral nutrition support.The main purpose it aims to answer are:1)Can immunonutrition therapy improve patients' dose-limiting toxicity(DLT) and DLT-free survival? 2)Can immunonutrition therapy improve patients' nutritional status and quality of life?
Official title: The Effects of Immunonutrition Therapy on the Nutritional Status, Immune Function, and Quality of Life of Locally Advanced Cervical Cancer Patients With Malnutrition: an Open-label Randomized Controlled Study
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-01-01
Completion Date
2026-12
Last Updated
2025-12-05
Healthy Volunteers
No
Conditions
Interventions
enteral immunonutrition
Patients in this group receives 2 bottles of immunonutrients per day (Impact, Nestlé, approximately 700 kcal).
standard oral enteral nutrition
Patients in the control group receives isoenergetic standard oral enteral nutrition ( emulsion or Nutrison).
Locations (1)
Cancer Hospital, Chinese Academy of Medical Sciences
Beijing, China