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Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition
Sponsor: University of Maryland, College Park
Summary
To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the researchers will assess memory, memory change over a nap and equivalent waking interval, sleep physiology of the nap, and brain structure and function (using Magnetic Resonance Imagining or MRI). Additionally, overnight sleep physiology will be assessed in all participants. Waves will take place approximately every 6 months. For all children, three waves will be collected. With these data, the researchers will address the following aims: * Examine neural markers that predict the sleep transition (Aim 1); * Examine changes in sleep-dependent memory processing (mnemonic discrimination) over both nap and overnight sleep intervals, across the sleep transition (Aim 2); * Examine changes in sleep microstructure in both nap and overnight sleep across the sleep transition (Aim 3) * Examine interrelations among brain, memory and sleep microstructure across the sleep transition (Aim 4)
Key Details
Gender
All
Age Range
36 Months - 60 Months
Study Type
INTERVENTIONAL
Enrollment
180
Start Date
2023-11-05
Completion Date
2028-06
Last Updated
2025-04-04
Healthy Volunteers
Yes
Conditions
Interventions
nap
Children are nap promoted
Locations (2)
University of Maryland
College Park, Maryland, United States
University of Massachusetts
Amherst, Massachusetts, United States