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RECRUITING
NCT06351098
NA

Longitudinal Investigation of Sleep, Memory, and Brain Development Across the Nap Transition

Sponsor: University of Maryland, College Park

View on ClinicalTrials.gov

Summary

To examine the relations between sleep (nap transitions, sleep physiology), memory, and brain development longitudinally, the researchers will assess n=180 children (in order to acquire n=152 usable data sets) who are 36-54 months of age and habitual nappers at enrollment. In each wave, the researchers will assess memory, memory change over a nap and equivalent waking interval, sleep physiology of the nap, and brain structure and function (using Magnetic Resonance Imagining or MRI). Additionally, overnight sleep physiology will be assessed in all participants. Waves will take place approximately every 6 months. For all children, three waves will be collected. With these data, the researchers will address the following aims: * Examine neural markers that predict the sleep transition (Aim 1); * Examine changes in sleep-dependent memory processing (mnemonic discrimination) over both nap and overnight sleep intervals, across the sleep transition (Aim 2); * Examine changes in sleep microstructure in both nap and overnight sleep across the sleep transition (Aim 3) * Examine interrelations among brain, memory and sleep microstructure across the sleep transition (Aim 4)

Key Details

Gender

All

Age Range

36 Months - 60 Months

Study Type

INTERVENTIONAL

Enrollment

180

Start Date

2023-11-05

Completion Date

2028-06

Last Updated

2025-04-04

Healthy Volunteers

Yes

Conditions

Interventions

BEHAVIORAL

nap

Children are nap promoted

Locations (2)

University of Maryland

College Park, Maryland, United States

University of Massachusetts

Amherst, Massachusetts, United States