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PO Methadone Ortho Outpatient
Sponsor: Keck School of Medicine of USC
Summary
The goal of this clinical trial is to learn if oral methadone given before surgery works to minimize post-operative pain and opioid usage. The main questions it aims to answer are: Does oral methadone improve post-operative pain scores as compared to standard treatment? Does oral methadone lead to reduced use of post-operative and post-discharge opioid usage as compared to the current standard treatment? Researchers will compare oral methadone to a placebo (a look-alike substance that contains no drug) to assess the questions above. Participants will: Receive either oral methadone or a look-alike placebo before surgery Receive standard intraoperative and immediate post-operative pain control at the anesthesiologist's discretion Be asked about their pain levels in the recovery area Keep a diary of pain and opioid usage over the first 2 days after surgery
Official title: Use of Single-Dose Oral Methadone for Pain Management in Outpatient Arthroscopic Hip and Knee Procedures
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-05-01
Completion Date
2025-12-15
Last Updated
2025-03-05
Healthy Volunteers
No
Interventions
Methadone group
5mg PO methadone for participants \<50kg or 10mg PO methadone for participants \>50kg
Placebo
sugar pill that is identical look-alike to study drug
Locations (1)
USC Healthcare Consultation 3
Los Angeles, California, United States