Clinical Research Directory

Inclusion Criteria: * For patients * Patient who has given free and informed consent in writing for inclusion in the non-interventional CART-BANK protocol, and orally for the CARTROG protocol, * Patients over 18 years of age at the time of inclusion, * Diagnosis of LDGCB, * Decision to treat with anti-CD19 CAR-T cells, * Patient affiliated to or benefiting from a social security scheme. * For healthy volunteers: * Given free and informed oral consent for inclusion in the CARTROG protocol, * Donor between 18 and 70 years of age at the time of inclusion, * No history of solid cancer or hematological malignancy, * No known chronic pathology (e.g. hypertension, diabetes, etc.) and no daily treatment, * No surgical treatment within the last 6 months. Exclusion Criteria: * Patients who do not meet all the inclusion criteria, * Pregnant or breast-feeding patient, * Patient unable to follow the procedures and/or frequency of visits planned in the trial, for psychological, family, social or geographical reasons, * Patient unable to consent freely to inclusion, under guardianship, curatorship or safeguard of justice.