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ACTIVE NOT RECRUITING
NCT06352775
NA

Calcium Carbonate on Labor Induction

Sponsor: Wake Forest University Health Sciences

View on ClinicalTrials.gov

Summary

The investigators aim to evaluate the safety and efficacy of administering calcium carbonate to laboring participants undergoing labor inductions. The investigators hypothesize that calcium carbonate is a low-risk preventative measure to decrease oxytocin induction time and dosage, decrease the rate of labor dystocia, decrease the rate of cesarean deliveries, and demonstrate no differences in maternal or neonatal safety outcomes.

Official title: The Effect of Calcium Carbonate on Labor Induction: A Pilot Study

Key Details

Gender

FEMALE

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

250

Start Date

2024-06-01

Completion Date

2026-12-30

Last Updated

2025-11-21

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Calcium Carbonate

We will be using it in routes and doses consistent with its approved uses. Per the drug label information for Calcium Carbonate USP 500 mg found in the US National Library of Medicine, adults may take 2-4 tablets as symptoms occur and if pregnant to not exceed 10 tablets in 24 hours. Therefore, using a dosing of 500mg every 4 hours will be well below that guidance. When both cervical ripening has been completed and the oxytocin administration begins, the calcium carbonate treatment group will be given calcium carbonate 500mg every 4 hours (not to exceed 10 tablets in 24 hours) until they deliver.

Locations (1)

Aurora Sinai Medical Center

Milwaukee, Wisconsin, United States