Clinical Research Directory

Inclusion Criteria: * Healthy male or female who is at least 18 years old. * Patients must sign an informed consent approved by the University of Louisville Human Studies Committee. Exclusion Criteria: * Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium. * Presence or history of osteonecrosis of jaws. * Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration. * Patients who have been treated with oral bisphosphonates for more than three years. * Patients with an allergy to any material or medication used in the study. * Patients who need prophylactic antibiotics * Previous head and neck radiation therapy. * Chemotherapy in the previous 12 months. * Patients on long term NSAID or steroid therapy. * Pregnant patients.