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RECRUITING
NCT06354712
PHASE2

Efficacy of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.

Sponsor: Mansoura University

View on ClinicalTrials.gov

Summary

A prospective, randomized, controlled, parallel clinical trial will be conducted at Clinical Oncology and Nuclear Medicine Center at Mansoura University Hospital to assess the efficacy of N-acetylcysteine in the prevention of radiotherapy induced oral mucositis in Head and Neck cancer patients.

Official title: Clinical Study Evaluating the Efficacy and Safety of N-acetylcysteine in Preventing Radiotherapy-Induced Oral Mucositis in Head and Neck Cancer Patients.

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2024-04-04

Completion Date

2025-03-01

Last Updated

2025-01-15

Healthy Volunteers

Yes

Interventions

DRUG

N-Acetyl-Cysteine with Institutional standard care

A potent antioxidant and anti-inflammatory drug (A precursor of the endogenous antioxidant glutathione)

DRUG

Institutional standard care

Benzydamine Mouthwash

Locations (1)

Clinical Oncology and Nuclear Medicine of Mansoura University Hospital

Al Mansurah, Egypt