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Effect of Dexmedetomidine on Oxygenation and Lung Mechanics
Sponsor: Cairo University
Summary
Dexmedetomidine is a selective α -2 agonist widely used in anesthesia for its sympatholytic, sedative and analgesic effects . Favorable respiratory effects in animals , and in selected human patient groups have been reported when using this agent .we investigated the effects of different doses of dexmedetomidine infusion on oxygenation
Official title: Effect of Different Does of Dexmedetomidine on Oxygenation and Lung Mechanics
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
176
Start Date
2024-04-01
Completion Date
2025-05-01
Last Updated
2024-04-10
Healthy Volunteers
Yes
Conditions
Interventions
GROUP Dexmedetomidine
Dexmedetomidine (Precedex) loadings of 1 μg/kg , then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .
GROUP B
Dexmedetomidine (Precedex) loadings of 0.5 μg/kg , then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .
GROUP C
Dexmedetomidine (Precedex) loadings of 0.25 μg/kg, then continuously at a rate of 0.2 μg/(kg/h) till the end of the operation .
Locations (1)
Cairo university
Cairo, Egypt