Clinical Research Directory

Inclusion Criteria: * Pregnant patients ≥34 weeks gestational age, for elective cesarean delivery under single-shot spinal anesthesia. * American Society of Anesthesiologists (ASA) Physical Status Class 2. * Patients ≥19 years of age. Exclusion Criteria: * Known history of pre-existing hypertension or hypertension disorders of pregnancy. * Having recently taken a medication to treat high blood pressure (e.g. labetolol, hydralazine, nifedipine) * Having recently taken a medication that could alter blood pressure, which could include beta those prescribed for anxiety (e.g. propranolol) or sedative pre-medication (e.g. midazolam, lorazepam). * Known allergic reaction or hypersensitivity to TXA or any other TXA homologue. * Elective cesarean delivery requiring general anesthesia or a neuraxial technique other than a single-shot spinal (e.g. Epidural or Combined Spinal Epidural). * Patients who are unable to give informed consent due to a language barrier as the study team only speaks English and will be unable to complete consent process and study procedure appropriately. * Patients arriving late to the surgical day care with \<90 min prior to scheduled cesarean delivery time resulting in potential delay for the operating room or inadequate time for consent and full execution of the protocol.