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The Efficacy and Palatability of Developed Polyethylene Glycol-based Formula for Children With Functional Constipation
Sponsor: Chulalongkorn University
Summary
This study aims to evaluate the efficacy and palatability of a developed polyethylene glycol-based formula compared with the standard polyethylene glycol (PEG) in the treatment of children with functional constipation for 8 weeks. Besides, we also aim to assess the side effects of a developed PEG-based formula as well as evaluate the change of rectal diameter from baseline at each visit between 2 groups.
Official title: Faculty of Medicine, Chulalongkorn University
Key Details
Gender
All
Age Range
6 Months - 18 Years
Study Type
INTERVENTIONAL
Enrollment
52
Start Date
2024-05-03
Completion Date
2026-12
Last Updated
2026-04-02
Healthy Volunteers
Yes
Conditions
Interventions
Local PEG4000
PEG-Chula is developed from PEG 4000 used at King Chulalongkorn Memorial Hospital with added sweetener and flavours. Children will be given PEG-Chula at a dose of 0.5 - 1 g/kg/day.
Commercial PEG4000
For commercial PEG, We use Forlax as the control group. Children will be given Forlax at a dose of 0.5 - 1 g/kg/day.
Locations (1)
Faculty of Medicine, Chulalongkorn University
Bangkok, Thailand