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Optimizing Ocular Outcomes: A Dual-armed Study for Periorbital Burn Management
Sponsor: Virginia Commonwealth University
Summary
The purpose of this study is to evaluate the effectiveness in using subcutaneous 5-FU/Kenalog \& topical Maxitrol Ophthalmic ointment as different therapeutic adjuncts in the prevention of pathologic remodeling after periorbital burns.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2026-02-28
Completion Date
2027-01
Last Updated
2026-01-16
Healthy Volunteers
No
Conditions
Interventions
Steroid/Antibiotic (Maxitrol)
Group one subjects receive topical maxitrol ophthalmic ointment twice daily for two weeks
5-FU/Kenalog
Group two undergoes treatment with a subcutaneous injection of a 5-fluorouracil (5-FU) and Kenalog (triamcinolone) combination (80/20 ratio, 0.3-0.5 mL per session) administered in four sessions, spaced two weeks apart, starting within 48 hours of hospital presentation