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APA and PAS Training for Gait Initiation in Parkinson's Disease
Sponsor: Chang Gung University
Summary
Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinson's disease (PD), alongside evaluating effective physical therapy methods. It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients, including balance and postural issues, cognitive function decline, and gait instability. Additionally, it notes that PD patients exhibit abnormal electrophysiological responses, indicating altered central excitability.
Official title: Gait-initiation Related APA Training in Individuals With Parkinson Disease -Explicit Training and Paired Associative Stimulation(PAS) Priming
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-06-13
Completion Date
2025-05-31
Last Updated
2024-04-12
Healthy Volunteers
Yes
Conditions
Interventions
Weight shift training and APA feedback
Use COP trajectory to train weight shift on force plate. To give APA visual feedback for subjects after weight shift training.
Paired associative stimulation
Use TMS combine ES to stimulate TA nerve and M1 cortical
Locations (1)
Chang Gung University
Taoyuan District, Taiwan