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NOT YET RECRUITING
NCT06365411

GEnomic Medicine in Kidney Transplantation Study

Sponsor: Western Sydney Local Health District

View on ClinicalTrials.gov

Summary

Investigator led, prospective, observational cohort study to detect genomic features which can predict outcomes following kidney transplantation. 1. Determine non-HLA genomic mismatches between donor-recipient pairs which impact kidney allograft survival following transplantation 2. Derive polygenic risk scores on pre-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction 3. Derive polygenic risk scores on post-transplant blood and/or kidney biopsy samples which predict kidney allograft dysfunction

Key Details

Gender

All

Age Range

18 Years - 80 Years

Study Type

OBSERVATIONAL

Enrollment

1000

Start Date

2025-06-03

Completion Date

2035-01-01

Last Updated

2025-03-28

Healthy Volunteers

No

Interventions

DIAGNOSTIC_TEST

Biomarker discovery and validation - with focus on genomic biomarkers

Biomarker discovery and validation - with focus on genomic biomarkers