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NCT06365775

Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss

Sponsor: Dan Bing

View on ClinicalTrials.gov

Summary

The goal of this observational study is to describe the multi-omics characteristics and to learn about the prognostic factors in patients with idiopathic sudden sensorineural hearing loss (SSNHL). The main problems it aims to deal with are: * if there is a difference in data of exome and targeted sequencing among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls * if there is a difference in the parameter of MRI among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls * to find out which factor from multi-omics data relates to outcomes of SSNHL * to develop the best prognostics model based on the multi-omics data. Participants will be received audiological tests, blood specimen collection and radiological examination. Researchers will explore the relationship between the multi-omics data and the prognosis and develop the predictive model.

Official title: Multi-omics Characteristics and Prognosis in Patients With Idiopathic Sudden Sensorineural Hearing Loss

Key Details

Gender

All

Age Range

4 Years - 65 Years

Study Type

OBSERVATIONAL

Enrollment

400

Start Date

2024-04-23

Completion Date

2026-11-23

Last Updated

2024-04-15

Healthy Volunteers

Yes