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Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.
Sponsor: Minia University Hospital
Summary
To assess the effect of Dexmedetomidine on serum Tau-217 protein and its relation to the incidence and severity of postoperative cognitive dysfunction in elderly patients undergoing major surgery under general anesthesia.
Official title: Effect of Dexmedetomidine on Serum Tau-217 Protein as a Biomarker for Post-operative Cognitive Dysfunction in Elderly Patients.
Key Details
Gender
All
Age Range
65 Years - Any
Study Type
INTERVENTIONAL
Enrollment
94
Start Date
2024-04
Completion Date
2026-03
Last Updated
2024-04-15
Healthy Volunteers
Yes
Conditions
Interventions
Dexmedetomidine Hydrochloride
dexmedetomidine effect in preventing postoperative cognitive dysfunction on elderly patients undergoing major surgery guided with serum Tau-217 protein.
normal saline
normal saline will be administrated in placebo group
Locations (1)
Arwa Essam
Minya, Egypt