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RECRUITING
NCT06366893
NA

Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants

Sponsor: Hospital Universitari Vall d'Hebron Research Institute

View on ClinicalTrials.gov

Summary

Docosahexaenoic acid (DHA) and arachidonic acid (AA) have a critical effect on the health and neuronal development of the fetus and newborn. Their deficiency has been associated with increased neonatal morbidity, especially in preterm newborns at birth. Direct DHA supplementation during the first few weeks of life could prevent this deficiency. The aim is to increase DHA levels in the red blood cell membrane while maintaining the fetal proportion to AA in preterm infants through enteral administration of DHA/AA in a safe, tolerated, and effective manner. This approach aims to avoid the decline in DHA/AA levels and the consequences of their deficiency. The study is a single-center, prospective, randomized, controlled, open-label study involving preterm infants admitted to the Neonatology Department of Vall d'Hebron University Hospital in Barcelona.

Official title: Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants. Single-center, Prospective, Randomized, Controlled, Open-label Clinical Trial

Key Details

Gender

All

Age Range

Any - 7 Days

Study Type

INTERVENTIONAL

Enrollment

80

Start Date

2024-03-04

Completion Date

2025-03-04

Last Updated

2024-04-19

Healthy Volunteers

Yes

Interventions

DIETARY_SUPPLEMENT

DHA/AA emulsion supplement for preterm infant

Enteral supplementation of DHA/AA emulsion

Locations (1)

Hospital Materno Infantil Vall d'Hebron

Barcelona, Spain