Clinical Research Directory
Browse clinical research sites, groups, and studies.
Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants
Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Summary
Docosahexaenoic acid (DHA) and arachidonic acid (AA) have a critical effect on the health and neuronal development of the fetus and newborn. Their deficiency has been associated with increased neonatal morbidity, especially in preterm newborns at birth. Direct DHA supplementation during the first few weeks of life could prevent this deficiency. The aim is to increase DHA levels in the red blood cell membrane while maintaining the fetal proportion to AA in preterm infants through enteral administration of DHA/AA in a safe, tolerated, and effective manner. This approach aims to avoid the decline in DHA/AA levels and the consequences of their deficiency. The study is a single-center, prospective, randomized, controlled, open-label study involving preterm infants admitted to the Neonatology Department of Vall d'Hebron University Hospital in Barcelona.
Official title: Enteral Supplementation With Docosahexaenoic Acid and Arachidonic Acid (DHA-AA) in Preterm Infants. Single-center, Prospective, Randomized, Controlled, Open-label Clinical Trial
Key Details
Gender
All
Age Range
Any - 7 Days
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2024-03-04
Completion Date
2025-03-04
Last Updated
2024-04-19
Healthy Volunteers
Yes
Conditions
Interventions
DHA/AA emulsion supplement for preterm infant
Enteral supplementation of DHA/AA emulsion
Locations (1)
Hospital Materno Infantil Vall d'Hebron
Barcelona, Spain