Clinical Research Directory

Inclusion Criteria: The subject must meet all of the following inclusion criteria at the time of enrolment: EITHER 1. Patient are at risk of hypoventilation and thus carbon dioxide retention. 2. Either 1. Under evaluation for treatment with non-invasive ventilation and maybe Long term oxygen treatment due to chronic obstructive pulmonary disease or 2. Under evaluation for non-invasive ventilation support due to Obesity hypoventilation syndrome or due to a neuromuscular disorder. OR 3. Healthy volunteers ALL subjects: 4. Subject must be 18 years or older 5. Subject must be able to give written informed consent Exclusion Criteria: 1. Known allergy to local anesthetics. 2. Participants should not have any kind of (direct or indirect) affiliation to Sensocure AS 3. Healthy volunteers: No heart-, lung-, or circulatory diseases, no bleeding disorder, no sleep disorders 4. Healthy volunteers should not have any kind of (direct or indirect) acquaintanceship to the investigators 5. Active smoker/use of snuff