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Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome
Sponsor: Osama Ahmed Elshafei
Summary
The goal of this clinical trial is to compare the efficacy of Ultrasound-Guided Platelet-Rich Plasma Injection versus Hydrodissection (using 2ml saline, 2ml dexamethasone and 1ml lidocaine) in the Treatment of Carpal Tunnel Syndrome. The main questions it aims to answer are: * Which modality is more effective in reducing symptoms and improving function in patients with Carpal tunnel syndrome * Asses safety profile of both methods Participants will: * Randomized to one of the two arms * Visit the clinic 1 and 3 months after intervention * Assessed for efficacy and safety of the intervention
Official title: A Prospective Comparative Study on the Efficacy of Ultrasound-Guided Platelet-Rich Plasma Injection Versus Hydrodissection in the Treatment of Carpal Tunnel Syndrome
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
64
Start Date
2024-01-16
Completion Date
2024-07-16
Last Updated
2024-04-16
Healthy Volunteers
No
Conditions
Interventions
ultrasound guided PRP injection
whole blood is initially collected in tubes that contain anticoagulants, such as citrate dextrose A to prevent platelet activation prior to its use. Then PRP is prepared by a differential centrifugation. Then 3ml of PRP will be delivered via the in-plane ulnar approach
ultrasound guided hydrodissection
5ml will be injected to detach the median nerve from the TCL (2ml saline, 2ml dexamethasone and 1ml lidocaine), the injectate will be delivered via the in-plane ulnar approach, and the median nerve will be hydrodissected from its undersurface while advancing the needle among the superficial surface of the median nerve and the TCL
Locations (1)
Mansoura University
Al Mansurah, Egypt