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The Role of Endogenous GIP in Glycosis Metabolism During Fasting
Sponsor: Frederikke Koefoed-Hansen
Summary
This research project aims to investigate the role of endogenous GIP during fasting. With the infusion of a GIP receptor antagonist (GIP\[3-30\]NH2), is it possible to selectively remove the effect of endogenous GIP, and thus describe its effects by comparing it with what happens during a saline infusion.
Official title: GA-18: The Role of Endogenous GIP in Glycosis Metabolism During Fasting
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2023-05-04
Completion Date
2025-12-31
Last Updated
2024-04-16
Healthy Volunteers
Yes
Conditions
Interventions
GIP[3-30]NH2
GIP\[3-30\]NH2 is the naturally occurring shorter (truncated) variant of GIP\[1-42\]. GIP\[3-30\]NH2 also stimulates the GIP receptor and therefore acts like a GIP receptorantagonist
Saline
Sodium chlorid with 0,5% human serum albumin.
Locations (1)
Gentofte Hospital
Hellerup, Denmark