Clinical Research Directory

Inclusion Criteria: * Pregnant woman over 18 years old * Woman whose gestational age is less than 30 weeks. * Having agreed to carry out an assay of anti-IFN alpha IgG auto-Ac before 30 weeks * Give birth in the inclusion center * Suffering from a pathology frequently associated with the presence of these anti-autoantibodies IFN alpha (lupus, severe COVID-19, myasthenia gravis, incontinentia pigmenti, hypoparathyroidism, adrenal insufficiency, diffuse candidiasis, Biermer's disease, dysthyroidism, type 1 diabetes, celiac disease, auto-thyroid disease immune system such as Graves' disease, Hashimoto's thyroiditis) or knowing its positive anti-IFN alpha autoantibody status * Affiliated with the Social Security system Exclusion Criteria: * Patient who underwent a blood transfusion less than 2 months ago * Patient who received an organ transplant * Patient undergoing immunotherapy, stem cell therapy and/or other malignancy maternal, under heavy treatment (chemotherapy) less than 6 months before inclusion